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Quick Info
Issue Date
February 2011
Category
Single Issue
Language
English
Peer Reviewed
Academic Journal
E-J Chem.,8(2), pp 547- 552
Introduction
A simple one-pot four-component synthetic method was reported for the preparation of tetrasubstituted imidazole derivatives from benzil, aromatic aldehydes, primary amines and ammonium acetate in the presence of Preyssler-type heteropoly acid catalyst. This method was proved to be ecobenign, easy work-up, convenient, relatively short reaction times and the products were isolated with high yields.
Keywords
Multi-component reactions (MCRs)
One-pot synthesis
tetrasubstituted imidazoles